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ORAC PREMIUM® High Potency Liquid Multi-Vitamins and Mineral Supplements |
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ORAC PREMIUM®HIGH-POTENCY LIQUID MULTI-VITAMIN & MINERAL SUPPLEMENTDesigned to support healthy structure and function of the human body by providing essential dietary nutrients.See Yourself Well ™*Orac Premium is Brunswick certified
ORAC PREMIUM® High Potency Liquid Multi-Vitamin and Mineral product in a pomegranate base provides premium health benefits and ensures maximum absorption and bioavailability of multivitamins and minerals. Each 1 ounce serving of ORAC PREMIUM® provides clinically backed and industry leading essential vitamins and select minerals, surpassing Health Canada and USDA recommended daily intakes for many of the ingredients in just one serving. This allows you to get your daily vitamins and minerals from a product that is also high in antioxidants. This liquid form in its pomegranate base tastes great and is an excellent replacement for multi-vitamin tablets, chews or capsules. It also ensures the highest possible rate of absorption. Each individual ingredient has been researched in studies in humans and animals. Based on clinical and pre-clinical literature, the formula provides ingredients shown to offer disease prevention in key areas such as heart disease, metabolic syndrome, certain cancers, type 2diabetes, cognitive function, age-related disorders, neurological disorders, and gastrointestinal disorders.
Lycopene
Lycopene is a carotenoid which cannot be used by the body to make vitamin A. It is the pigment which gives some fruits and vegetables, such as tomatoes, pink grapefruit, and watermelons, their pink to red colour. Most of the lycopene in the diet of North Americans comes from heated tomatoderived products. Epidemiological evidence shows that consumption of 6.5mg (women) and 12mg (men) lycopene decreases the risk of lung cancer in nonsmoking middle aged to older adults (1). Furthermore, consumption of greater than 6mg lycopene daily is associated with a lower risk of developing prostate cancer (2-6). Additional research in men with prostate neoplasia shows that intake of 8mg lycopene daily prevents or delays progression to prostate cancer (7).Since dietary lycopene influences levels of lycopene in the body, increased serum levels of dietary lycopene has also been linked with decreased risk of some types of cancer. Furthermore, studies show that lycopene is able to prevent the oxidation of low density lipoprotein cholesterol, reducing risk of atherosclerosis. Lycopene’s ability to reduce the risk of cancer, and its conclusive role in cardiovascular disease risk management, is due to its anti-oxidant, or freeradical scavenging ability.
Lutein
Lutein is also a carotenoid found in relatively high levels in the blood, eyes and fat tissue,and its levels in the body are also dependant on the amount consumed in the diet. Lutein also has anti-oxidant properties. Epidemiological evidence from human studies shows that higher consumption of dietary lutein is associated with a reduced risk of developing colorectal cancer, as well as age-related macular degeneration and cataracts, two serious eye disorders (8-13). Intakes of approximately 6-10mg lutein daily are associated with a reduced risk in these eye disorders. Research in humans further shows that lutein supplements (10mg daily) for one year improved many of the symptoms associated withthis eye disease (14).
Pomegranate
Pomegranate fruit and juice contain high levels of plant polyphenols such as anthocyanins, leucoanthocyanins, catechins and flavonols; the punicalagins being the major polyphenols present. Pomegranate juice contains greater amounts of polyphenols than red wine, blueberry, cranberry, or green tea (15). Intake of plant polyphenols is associated with increased antioxidant status and polyphenol levels in a food product contribute to its total antioxidant activity, or oxygen radical absorbance capacity (ORAC). The ORAC of pomegranate is higher than that of red wine or green tea (16, 17), traditionally suggested to be high antioxidant food products. The liquid multiitamin and mineral supplement High Potency Multi-Vitamins & Minerals contains 5000 ORAC units per fluid ounce serving. In a recent study in humans, a one-time intake of 800mg of pomegranate extract resulted in an increase in ellagic acid, and some of its metabolites, in blood (18). The C(max) (maximum concentrations) was 33 ng/mL one hour after consumption. It was determined that the antioxidant capacity measured with the ORAC assay was increased with a maximum effect of 32% after 30 minutes. This shows that consumption of high ORAC pomegranate is capable of increasing ORAC status of the blood. In a study by Cao et al (19) individuals who increased the ORAC potential of their diet to approximately 3300 ORAC units were able to increase plasma ORAC values. Furthermore, 5000 ORAC units as found in one fluid ounce serving of See Yourself Well™ High Potency Multi-Vitamins & Minerals much greater than that found in one serving of the majority of foods regularly consumed in North America (20).Pomegranate fruit juice has been studied in in vitro, animal and human studies. In an animal study, pomegranate juice-fed mice were found to have decreased oxidative stress in bodily fluids and a reduced size in atherosclerotic lesions (17). Negative modifications of low density lipoprotein cholesterol and levels of low density lipoprotein cholesterol were also decreased in these mice. Also in mice, pomegranate juice resulted in increased cholesterol efflux (21). Antioxidant activity and reduced atherosclerotic lesions nitric oxide synthetase activity in endothelial cells of the blood vessels, thus increasing the availability of nitric oxide, which acts as a vasodilator (22). Pomegranate juice is a more potent inhibitor of superoxide anion-mediated disappearance of nitric oxide, than Concord grape juice, blueberry juice or red wine, in vitro (23). Dietary pomegranate juice consumption has been investigated in atherosclerotic patients with carotid artery stenosis (24). Ten patients were supplemented with pomegranate juice for one year. During this time, the carotid intima-mediathickness, a measurement of atherosclerosis, increased by 9% in the control group. In the pomegranate juice group, however, there was a 30% reduction in intimal thickness. Furthermore, there was a 90% reduction in oxidized low density lipoprotein cholesterol in these patients, and their low density lipoprotein cholesterol was 59% less susceptible to oxidation. The patients total antioxidant status was increased. Also of interest was the decreased blood pressure in
References available on request. |
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